Peptides Clarified

Directory

Treatments

Plain-language profiles of peptides, GLP-1 medications, hormones, and longevity-adjacent treatments. Each shows regulatory status, evidence level, and sources.

11 treatments

  • Recovery & performance

    BPC-157

    A synthetic 15-amino-acid peptide marketed for tissue healing and recovery. It is not FDA-approved for any use, and human clinical evidence is essentially absent.

    Not FDA-approvedEvidence: Preclinical only
    Last reviewed (yesterday)
  • GLP-1 & metabolic

    Compounded semaglutide

    Semaglutide prepared by compounding pharmacies rather than the FDA-approved manufacturer. The molecule may be the same, but these specific products are not FDA-reviewed or approved.

    Compounded (not FDA-approved)Evidence: Insufficient
    Last reviewed (yesterday)
  • GLP-1 & metabolic

    Dulaglutide

    A once-weekly injectable GLP-1 receptor agonist FDA-approved for type 2 diabetes and to reduce cardiovascular events in adults with diabetes.

    FDA-approvedEvidence: Established
    Last reviewed (yesterday)
  • GLP-1 & metabolic

    Liraglutide

    A once-daily injectable GLP-1 receptor agonist FDA-approved for type 2 diabetes (Victoza) and chronic weight management (Saxenda), including in adolescents 12 and older.

    FDA-approvedEvidence: Established
    Last reviewed (yesterday)
  • Longevity-adjacent

    Metformin

    A long-established oral medication FDA-approved for type 2 diabetes. It is studied off-label for aging-related outcomes but is not FDA-approved for longevity.

    Approved (other use)Evidence: Limited
    Last reviewed (yesterday)
  • Longevity-adjacent

    NAD+ and NAD precursors (NMN, NR)

    NAD+ is a coenzyme central to metabolism; NMN and NR are precursors sold as supplements to raise NAD+ for longevity and energy claims. They are not FDA-approved drugs.

    Not FDA-approvedEvidence: Limited
    Last reviewed (yesterday)
  • Longevity-adjacent

    Rapamycin (Sirolimus)

    An mTOR-inhibiting drug FDA-approved to prevent kidney transplant rejection and to treat LAM. It attracts off-label longevity interest from animal studies but is not FDA-approved for aging.

    Approved (other use)Evidence: Preclinical only
    Last reviewed (yesterday)
  • GLP-1 & metabolic

    Semaglutide

    A GLP-1 receptor agonist FDA-approved for type 2 diabetes (Ozempic/Rybelsus) and chronic weight management and cardiovascular risk reduction (Wegovy).

    FDA-approvedEvidence: Established
    Last reviewed (yesterday)
  • Peptide therapy

    Tesamorelin

    A growth-hormone-releasing factor analog and the only FDA-approved medication to reduce excess abdominal fat in adults with HIV-associated lipodystrophy.

    FDA-approvedEvidence: Established
    Last reviewed (yesterday)
  • Hormone therapy

    Testosterone therapy (TRT)

    Prescription testosterone (injections, gels, patches, pellets) FDA-approved to treat hypogonadism in males from identifiable medical conditions — not age-related low testosterone alone.

    FDA-approvedEvidence: Established
    Last reviewed (yesterday)
  • GLP-1 & metabolic

    Tirzepatide

    A dual GIP and GLP-1 receptor agonist given by weekly injection, FDA-approved for type 2 diabetes (Mounjaro) and chronic weight management and obstructive sleep apnea with obesity (Zepbound).

    FDA-approvedEvidence: Established
    Last reviewed (yesterday)